Sunday, 12 August 2012

Mars as you've never seen it:

After releasing exciting images of Mars, NASA's Curiosity rover is undergoing a crucial four day ‘brain transplant’.
Engineers will update the rover’s software which is currently in its flight stage to prepare it for its further missions on Mars, NASA said.
After successfully landing on the Red Planet on August 5, the rover produced incredible pictures showing  exactly what you would see if you were standing on the surface of Mars on a late afternoon.
During the update, engineers will add two crucial functions to Curiosity – the ability to drive over the planet’s rocky terrain and the ability to use the geochemistry lab’s sampling system.






remark:the NEWS comes from google

Thursday, 9 August 2012

Allergic diseases ‘gender related’ news

Professor Hasan Arshad, a consultant in allergy and immunology at Southampton General Hospital, found that allergies such as asthma and eczema were gender-related and not simply hereditary.

“We have known for decades that allergy runs in the family and many thought that maternal effect was greater than paternal effect due to a mother’s closeness to her child, but we have discovered the inheritance is from mother to daughter and father to son,” said Prof Arshad.

His team assessed 1,456 patients recruited from birth 23 years ago and found the risk of asthma in boys was only increased if their fathers suffered from the condition while, if mothers had asthma, it doubled the risk in their daughters but not sons.

The research, published in the Journal of Allergy and Clinical Immunology and funded by the National Institute of Health in the US, also showed maternal eczema led to a 50% increased risk of eczema in girls, while paternal eczema did the same for boys.

“In the past, studies looking at the effect of parental allergy on children have not split their samples according to the sex of the child, having assumed the mother and father influence is identical in males and females,” explained Prof Arshad, who is also chairman of allergy and immunology at the University of Southampton.

“Now, with these groundbreaking findings, we should see a change in the way we assess a child’s risk of disease, asking girls for the allergy history of their mother and boys for that of their father.

“This work also opens up novel areas for further research in the genetics of allergy as to why this sex dependent effect occurs and, if we can find the reason, we can try to find a way of preventing sex-specific disease,” he added.

Bevis Man, from the British Skin Foundation charity, welcomed the research. “This news is very interesting and sheds light on how eczema from parents can ultimately affect their children,” he said. “There has been a great deal of research over the past 10 years focusing on the genetics of eczema and the genetic defects that may lead to the development of eczema.

“This news will hopefully spur a new wave of research looking into the differences between the sexes and the role in which a child is likely to develop the disease. Although a large proportion of children will simply ‘grow out’ of eczema, for many adults this is not the case, so any new developments in understanding the disease are most welcome.”





remark:the NEWS comes from google.

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Tuesday, 7 August 2012

The power of intermittent fasting

I'd always thought of fasting as something unpleasant, with no obvious long term benefits. So when I was asked to make a documentary that would involve me going without food, I was not keen as I was sure I would not enjoy it.

But the Horizon editor assured me there was great new science and that I might see some dramatic improvements to my body. So, of course, I said, "yes".

I am not strong-willed enough to diet over the long term, but I am extremely interested in the reasons why eating less might lead to increased life span, particularly as scientists think it may be possible to get the benefits without the pain.
How you age is powerfully shaped by your genes. But there's not much you can do about that.

Calorie restriction, eating well but not much, is one of the few things that has been shown to extend life expectancy, at least in animals. We've known since the 1930s that mice put on a low-calorie, nutrient-rich diet live far longer. There is mounting evidence that the same is true in monkeys.

Growth hormone
The world record for extending life expectancy in a mammal is held by a new type of mouse which can expect to live an extra 40%, equivalent to a human living to 120 or even longer.

It has been genetically engineered so its body produces very low levels of a growth hormone called IGF-1, high levels of which seem to lead to accelerated ageing and age-related diseases, while low levels are protective.


Professor Longo has investigated growth hormone deficiency in humans
A similar, but natural, genetic mutation has been found in humans with Laron syndrome, a rare condition that affects fewer than 350 people worldwide. The very low levels of IGF-1 their bodies produce means they are short, but this also seems to protect them against cancer and diabetes, two common age-related diseases.

The IGF-1 hormone (insulin-like growth factor) is one of the drivers which keep our bodies in go-go mode, with cells driven to reproduce. This is fine when you are growing, but not so good later in life.

There is now evidence suggesting that IGF-1 levels can be lowered by what you eat. Studies on calorie restrictors suggest that eating less helps, but it is not enough

As well as cutting calories you have to cut your protein intake. Not entirely - that would be a very bad idea. It's about sticking to recommended guidelines, something most of us fail to do.

The reason seems to be that when our bodies no longer have access to food they switch from "growth mode" to "repair mode".

As levels of the IGF-1 hormone drop, a number of repair genes appear to get switched on according to ongoing research by Professor Valter Longo of the University of Southern California.

Intermittent fasting
One area of current research into diet is Alternate Day fasting (ADF), involving eating what you want one day, then a very restricted diet (fewer than 600 calories) the next, and most surprisingly, it does not seem to matter that much what you eat on non-fast days.

Dr Krista Varady of the University of Illinois at Chicago carried out an eight-week trial comparing two groups of overweight patients on ADF.

"If you were sticking to your fast days, then in terms of cardiovascular disease risk, it didn't seem to matter if you were eating a high-fat or low-fat diet on your feed (non-fast) days," she said.

I decided I couldn't manage ADF, it was just too impractical. Instead I did an easier version, the so-called 5:2 diet. As the name implies you eat normally 5 days a week, then two days a week you eat 500 calories if you are a woman, or 600 calories, if you are a man.

There are no firm rules because so far there have been few proper human trials. I found that I could get through my fast days best if I had a light breakfast (scrambled eggs, thin slice of ham, lots of black tea, adding up to about 300 calories), lots of water and herbal tea during the day, then a light dinner (grilled fish with lots of vegetables) at night.
On my feed days I ate what I normally do and felt no need to gorge.

I stuck to this diet for 5 weeks, during which time I lost nearly a stone and my blood markers, like IGF-1, glucose and cholesterol, improved. If I can sustain that, it will greatly reduce my risk of contracting age-related diseases like cancer and diabetes.

Current medical opinion is that the benefits of fasting are unproven and until there are more human studies it's better to eat at least 2000 calories a day. If you really want to fast then you should do it in a proper clinic or under medical supervision, because there are many people, such as pregnant women or diabetics on medication, for whom it could be dangerous.

I was closely monitored throughout and found the 5:2 surprisingly easy. I will almost certainly continue doing it, albeit less often. Fasting, like eating, is best done in moderation.

































































remark:the NEWS comes from google.

Monday, 6 August 2012

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    GSM/GPRS/EDGE 850/900/1800/1900MHz
    2 X 2 MiMo & MicroSD Card slot(32G)
    Internal antenna and external antenna connector
    OS: Windows XP/Vista/7,Linux, Mac OS.

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Sunday, 5 August 2012

Chemotherapy can 'encourage cancer', claims new research

Some anti-cancer drugs have been proven to damage the DNA of normal tissue, causing it to secrete chemicals and resist treatment.
But far from being seen as a negative development in the battle against cancer, scientists hope the discovery will help enhance treatment.
‘The next step is to find ways to target these resistance mechanisms to make chemotherapy more effective,’ said Prof Fran Balkwill of Cancer  Research UK.
‘Cancer treatments don’t just affect cancer cells but can also target cells in and around tumours.
‘Sometimes this can be good – for instance, chemotherapy can stimulate surrounding healthy immune cells to attack tumours.
‘But this work confirms that healthy cells surrounding tumours can also make them resistant to treatment.’
Dr Peter Nelson, who carried out the research at the Fred Hutchinson Cancer Research Centre in Seattle, explained: ‘Cancer cells inside the body live in a very complex environment or neighbourhood.
‘Where the tumour cell resides and who its neighbours are influence its response to therapy.’
The research, which was published in the online journal Nature Medicine, looked at cancer cells taken from prostate, breast and ovarian cancer patients who had been receiving chemotherapy.
Blocking the treatment response of fibroblasts – a type of normal, non-cancerous cell found near tumours – could be one way to improve the effectiveness of chemothe

Thursday, 2 August 2012

Mom's genes may explain why women outlive men

An evolutionary "loophole" might explain why males of many species live shorter lives than their female counterparts, a new study finds.
The loophole lies in the mitochondria, the energy-generating parts of our cells. The mitochondria have their own DNA, separate from the DNA that resides in the nucleus of the cell that we usually think of when we think of the genome. In almost all species, the mitochondria DNA is passed down solely from mother to child, without input from dad.
This direct line of inheritance may allow harmful mutations to accumulate, according to a new study detailed today (Aug. 2) in the journal Current Biology. Ordinarily, natural selection helps keep harmful mutations to a minimum by ensuring they're not passed down to offspring. But if a mitochondrial DNA mutation is dangerous only to males and doesn't harm females, there's nothing to stop mom from passing it to her daughters and sons.
"If a mitochondrial mutation pops up that is benign in females, or a mutation pops up that is beneficial to females, this mutation will slip through the gates of natural selection and go through to the next generation," said study researcher Damian Dowling, an evolutionary biologist at Monash Univeristy in Australia.